Synthesis of fatty acid anhydrides by reaction with dicyclohexylcarbodiimide

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Synthesis of fatty acid anhydrides by reaction with dicyclohexylcarbodiimide.

A simple method is described for the preparation of caprylic, palmitic, stearic, and oleic anhydrides. Reaction of the free fatty acid and dicyclohexylcarbodiimide in carbon tetrachloride at room temperature gives the corresponding anhydrides in high yield (87-94%).

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ژورنال

عنوان ژورنال: Journal of Lipid Research

سال: 1966

ISSN: 0022-2275

DOI: 10.1016/s0022-2275(20)39603-6